低密度脂蛋白受体
内分泌学
内科学
基因剔除小鼠
载脂蛋白E
血脂异常
基因敲除
胆固醇
脂蛋白
载脂蛋白B
生物
家族性高胆固醇血症
极低密度脂蛋白
医学
受体
疾病
糖尿病
生物化学
基因
作者
Amandine Chaix,Terry Lin,Bastian Ramms,Roy G. Cutler,T LE,Catherine Lopez,Phuong Miu,Antônio F. M. Pinto,Alan Saghatelian,Martin P. Playford,Nehal N. Mehta,Mark P. Mattson,Philip L.S.M. Gordts,Joseph L. Witztum,Satchidananda Panda
标识
DOI:10.1161/atvbaha.124.320998
摘要
In a preclinical animal model, TRF is effective in both the prevention and regression of atherosclerosis in LDLR knockout mice. The results suggest TRF alone or in combination with a low-cholesterol diet can be a lifestyle intervention for reducing cardiovascular disease risk in humans.
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