Artificial Lithium Channels Built from Polymers with Intrinsic Microporosity

In sharp contrast to numerous artificial potassium channels developed over the past decade, the study of artificial lithium-transporting channels has remained limited. We demonstrate here the use of an interesting class of polymers with intrinsic microporosity (PIM) for constructing artificial lithium channels. These PIM-derived lithium channels show exceptionally efficient (γ_Li ⁺>40 pS) and highly selective transport of Li⁺ ions, with selectivity factors of>10 against both Na⁺ and K⁺. By simply adjusting the initial reaction temperature, we can tune the transport property in a way that PIMs synthesized at initial reaction temperatures of 60 °C and 80 °C exhibit improved transport efficiency and selectivity, respectively, in the dioleoyl phosphatidylcholine membrane.