清脆的
合成生物学
计算生物学
生物
计算机科学
效应器
信号转导
重编程
细胞生物学
基因
遗传学
作者
Yuchen Liu,Yonghao Zhan,Zhicong Chen,Anbang He,Jianfa Li,Hanwei Wu,Li Liu,Chengle Zhuang,Junhao Lin,Xiaoqiang Guo,Qiaoxia Zhang,Weiren Huang,Zhiming Cai
出处
期刊:Nature Methods
[Nature Portfolio]
日期:2016-09-05
卷期号:13 (11): 938-944
被引量:169
摘要
The integration of ligand-responsive riboswitches with single guide RNAs allows Cas9–effector fusions to be targeted in response to ligands and thereby translate a cellular signal into a downstream readout of choice.
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