Synthesis and in vitro Anti-tumor Activity of Some New Sebacoyl Chloride Based Heterocycles

Background: N-Heterocycles are of special interest because, many natural and synthetic bioactive compounds are found to be N-containing heterocycles and they constitute an important class of pharmacophores in medicinal chemistry. Recently, 1,2,3-triazoles have been found to possess a vast range of vital applications in the agrochemical, pharmaceutical, and materials field. In addition, various compounds of the 1,2,3-triazole family have shown a broad spectrum of biological properties such as antibacterial, and anti-HIV activity. 1,3,4- Oxadiazoles are important oxygen and nitrogen containing heterocyclic compounds, they possess desirable electronic and charge-transport properties. Keywords: Sebacoyl chloride, acid chloride, decanedihydrazide, azole, N-heterocycles, anti-tumour activity., Sebacoyl chloride, acid chloride, decanedihydrazide, azole, N-heterocycles, anti-tumour activity.