Objective: To evaluate of laparoscopic treatment of endometriosis in surgical techniques and clinical results. Methods: 38 patients with endometriosis of our hospital from January 2008 to January 2010 were randomly divided into observation group of 22 patients (laparoscopic surgery) and control group of 16 patients (abdominal surgery). The therapeutic effect of the two groups were compared.Results:Two groups of bleeding, anal exhaust time, wound healing time, postoperative hospital stay was compared, the differences were significant (P0.05), compared the pregnancy rate between the two groups,the difference was significant (P0.05).Conclusion:Laparoscopic treatment of endometriosis has significant effect,it is worthy of clinical application.