A new HMG-COA reductase inhibitor:rosuvastatin

Rosuvastatin is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor used for improving the lipid profile of patients with heterozygous or homozygous familial hypercholesterolaemia, hypertriglyceridaemia or mixed dyslipidaemia. Rosuvastatin has a low propensity for drug interactions and is well tolerated in clinical trials. The pharmacodynamics, pharmacokinetics, drug interactions, pharmacotherapy and safety profiles of rosuvastatin are presented.