In vivo Three-photon Imaging of Brain Activity from Cortical and Subcortical Neurons in Intact Mouse Brain
作者
Dimitre G. Ouzounov,Tianyu Wang,Nicholas G. Horton,Jean C. Cruz Hernández,Danielle D. Feng,Nozomi Nishimura,Chris Xu
出处
期刊:日期:2015-01-01卷期号:9: BrW3B.5-BrW3B.5
标识
DOI:10.1364/boda.2015.brw3b.5
摘要
We demonstrate three-photon microscopy (3PM) at 1300-nm-excitation for imaging neuronal activity through the entire neocortex and as deep as the hippocampal stratum pyramidale (SP) layer of the living adult mouse brain using genetically-encoded calcium indicators.