Analysis of the level of T lymphocytes subpopulations in the peripheral blood of patients with nasopharyngeal carcinoma

Objective:To analyze the characteristics,associated factors and clinical significance of the level of T lymphocytes subpopulations in the peripheral blood of the patients with nasopharyngeal carcinoma.Methods:T lymphocytes of 66 nasopharyngeal carcinoma patients and the change of T lymphocytes subpopulations in patients were detected,and the results were compared with those of the normal control.Results:The CD4+T cells and CD4+/CD8+ ratio in patients with nasopharyngeal carcinoma were significantly lower than that in the control group(P0.01).Compared with the control group the CD8+T cells in patients with tumor were significantly higher.Conclusions:The cellular immune function of the patients with nasopharyngeal carcinoma was lowered.Detecting T lymphocyte subpopulations' expression in peripheral blood in patients with nasopharyngeal carcinoma is of clinical value for assessing cellular immune function,treatment and prognosis of disease.