We present a case of 58-year-old male patient who underwent post-operative spondylodiscitis. We assessed the correlation between clinical symptoms and blood test results, and serial MRI findings in a patient with postoperative infectious spondylitis who was on treatment. Despite its effectiveness in the diagnosis of infectious spondylitis, MRI findings exhibited slightly delayed correlation with the patient's clinical symptoms and blood test results. Therefore, when treating postoperative infectious spondylitis patients, MR imaging should not be an independent tool, but should be complemented by other examinations and assessment of clinical symptoms.