Enhancing Circular Dichroism Signals with Vector Beams.

Circular dichroism (CD) is broadly employed for distinguishing molecular chiralities. However, its practical application is often limited by the weak magnitude of chiral signal. We propose to use azimuthally and radially polarized vector beams to probe CD spectra. By taking advantage of the strong longitudinal components of the vector beams, the transmitted light can be detected in the radial direction. The resulting CD signal is several orders of magnitude stronger than conventional CD signal with plane waves. Quantitative analysis and numerical simulations show that the enhancement factor is independent of molecular properties and can be increased by decreasing the path length of the sample cuvette and the interaction cross section between the light beam and molecular sample. The proposed novel CD spectroscopy is feasible with the current optical technology.