精神分裂症(面向对象编程)
双相情感障碍
地塞米松抑制试验
萧条(经济学)
内科学
锂(药物)
研究诊断标准
精神科
双相性疾病
内分泌学
精神病
心理学
内源性抑郁症
医学
地塞米松
内生
狂躁
经济
宏观经济学
标识
DOI:10.1016/0165-0327(84)90018-1
摘要
In two separate studies, we have obtained plasma levels of GABA in 134 psychiatric patients and 22 normal controls. Patients with a unipolar affective disorder had levels significantly lower than control (n = 58) as did patients with alcoholism (n = 10). Patients with a bipolar affective disorder had levels significantly higher than control when manic (n = 28) and also when euthymic on lithium prophylaxis (n = 17), but levels in the control range when depressed (n = 4). Patients with schizophrenia demonstrated a high degree of variability in their levels of plasma GABA but were not statistically different from control (n = 36). Patients with unipolar depression who received a dexamethasone suppression test had no correlation between nonsuppression of cortisol secretion and plasma levels of GABA. Diagnostic and research implication of plasma GABA in psychiatric illness are discussed.
科研通智能强力驱动
Strongly Powered by AbleSci AI