Factors of Risk in the Development of Coronary Heart Disease—Six-Year Follow-up Experience

Article1 July 1961Factors of Risk in the Development of Coronary Heart Disease—Six-Year Follow-up ExperienceThe Framingham StudyWILLIAM B. KANNEL, M.D., THOMAS R. DAWBER, M.D., F.A.C.P., ABRAHAM KAGAN, M.D., F.A.C.P., NICHOLAS REVOTSKIE, M.D., JOSEPH STOKES III, M.D.WILLIAM B. KANNEL, M.D.Search for more papers by this author, THOMAS R. DAWBER, M.D., F.A.C.P.Search for more papers by this author, ABRAHAM KAGAN, M.D., F.A.C.P.Search for more papers by this author, NICHOLAS REVOTSKIE, M.D.Search for more papers by this author, JOSEPH STOKES III, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-1-33 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIncreasingly reliable estimates of the prevalence and incidence of coronary heart disease (CHD) emphasize the importance of this disease as a contemporary health hazard. Cardiovascular disease is now the leading cause of death, with coronary heart disease accounting for two-thirds of all heart disease deaths. While advances in the diagnosis and therapeutic management of CHD have been made in the past decade, no important reduction in morbidity and mortality from CHD has occurred. This is apparent in the relatively slight increase in life expectancy at age 40 which has been achieved in the past several decades, while life expectancy at...References1. DAWBERMOOREMANN TRFEGV: II. Coronary heart disease in the Framingham Study. Amer. J. Public Health 47: 4, 1957. CrossrefGoogle Scholar2. DAWBERMEADORSMOORE TRGFFE: Epidemiological approaches to heart disease: the Framingham Study. Amer. J. Public Health 41: 279, 1951. CrossrefGoogle Scholar3. DAWBERMOORE TRFE: Longitudinal study of heart disease in Framingham, Massachusetts. An interim report: research in public health. 1951 Annual Conference of the Milbank Memorial Fund. Milbank Mem. Fund Quart. 1952. 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CORNFIELDGORDONSMITH JTW: Quantal response curves for experimentally uncontrolled variables. Proceedings of the 32nd Session of the International Statistical Institute, Tokyo, 1960. To be published. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Framingham, MassachusettsReceived for publication April 19, 1961.From the Heart Disease Epidemiology Study, Framingham, Mass., and the National Heart Institute, National Institutes of Health, Public Health Service, U. S. Department of Health, Education, and Welfare, Washington, D. C.Presented at the Forty-second Annual Session, The American College of Physicians, May 8-12, 1961, Bal Harbour, Fla.Requests for reprints should be addressed to Thomas R. Dawber, M.D., F.A.C.P., Medical Director, Heart Disease Epidemiology Study, 25 Evergreen St., Framingham, Mass. 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