One-pot synthesis of 1,3-oxazin-4-ones through an Ir-catalyzed mild formal condensation reaction of secondary amides with acyl chlorides

Bicyclic 2,3,6,7-tetrahydrocyclopenta[ e ]-1,3-oxazin-4-ones/2,3,5,6,7,8-hexahydro-4 H -benzo[ e ]-1,3-oxazin-4-ones and monocyclic 1,3-oxazin-4-ones were prepared via an Ir-catalyzed one-pot reaction of secondary amides with acyl chlorides in good yields.