医学
先天性膈疝
生活质量(医疗保健)
规范性
儿科
纵向研究
健康相关生活质量
人口学
内科学
怀孕
胎儿
哲学
遗传学
护理部
疾病
认识论
病理
社会学
生物
作者
Isabel Sreeram,J. Marco Schnater,Joost van Rosmalen,Suzan C M Cochius-den Otter,N. Peters,Robbert J. Rottier,Saskia J. Gischler,René Wijnen,Hanneke IJsselstijn,André B. Rietman
出处
期刊:Pediatrics
[American Academy of Pediatrics]
日期:2023-05-18
卷期号:151 (6)
被引量:2
标识
DOI:10.1542/peds.2022-060385
摘要
OBJECTIVES To longitudinally evaluate self-reported health status (HS) and quality of life (QoL) in 8- and 12-year-old survivors of congenital diaphragmatic hernia (CDH). We hypothesized that HS would improve with age—as associated health problems tend to decline—whereas QoL would decrease, as the children start to compare themselves with peers. METHODS Self-reported HS and QoL of 133 children born between 1999 and 2013 who had joined our standardized follow-up program were routinely assessed at the ages of 8 and 12 with generic, internationally validated, standardized instruments. Longitudinal evaluation of total and subscale scores was performed using general linear model analyses. In addition, we compared these scores to sex- and age-specific normative data. RESULTS Between ages 8 and 12, boys born with CDH perceived a decline in HS (mean difference −7.15, P < .001). Self-reported QoL did not change over time in both boys and girls. At both ages, HS was significantly lower than that of healthy peers (effect size = 0.71, P = .001 for boys, and effect size = 0.69, P = .003 for girls), whereas differences in QoL were small. CONCLUSIONS Children born with CDH are at risk for declining HS between 8 and 12 years, but not QoL, compared with healthy peers. Given that children born with CDH tend to grow into deficits, our findings highlight the need for continued somatic and psychological assessments in adolescent and adult CDH survivors.
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