达布科
区域选择性
化学
吡啶
废止
串联
三氟甲基
组合化学
有机化学
辛烷值
催化作用
材料科学
烷基
复合材料
作者
Qi Yang,Shuntao Huang,Yin Li,Zhuoyu Wang,Xuebing Chen,Chao Huang
摘要
A microwave-assisted DABCO-promoted strategy for the regioselective synthesis of pyrrolo[3,4-b]pyridine-4-one derivatives has been developed from the [3 + 3] annulation of α-aminomaleimide with substituted ethyl 2-butynoate. The characteristic features of this methodology include operational simplicity, high regioselectivity, metal-free reaction conditions, and short reaction times. The potential utility of these methods in biological chemistry and medicinal science applications is highlighted.
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