医学
心脏病学
内科学
冠状动脉疾病
心绞痛
冠状动脉
病理生理学
动脉
冠状动脉造影
疾病
缺血
冠状动脉粥样硬化
心肌梗塞
作者
Sonal Pruthi,Emaad Siddiqui,Nathaniel R. Smilowitz
标识
DOI:10.1016/j.ccl.2023.07.003
摘要
Ischemic heart disease (IHD) affects more than 20 million adults in the United States. Although classically attributed to atherosclerosis of the epicardial coronary arteries, nearly half of patients with stable angina and IHD who undergo invasive coronary angiography do not have obstructive epicardial coronary artery disease. Ischemia with nonobstructive coronary arteries is frequently caused by microvascular angina with underlying coronary microvascular dysfunction (CMD). Greater understanding the pathophysiology, diagnosis, and treatment of CMD holds promise to improve clinical outcomes of patients with ischemic heart disease.
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