There was a palpable buzz and energy at this year’s annual meeting of the American Society of Gene and Cell Therapy (ASGCT) held in Washington, DC. Record crowds swamped the meeting locale such that, in many cases, it was literally standing room only. Of course, not a bad problem to have for a field that has seen its fair share of ups and downs. The annual Editorial Board meeting of the Molecular Therapy journals was actually held in one of three tents set up in the hotel courtyard to accommodate the greater than expected number of meeting attendees.