Objective : To develop and examine psychometric properties of the Psychological Flexibility Scale for Adolescents. Materials and methods : Literature review was conducted in order to develop items of the Psychological Flexibility Scale for Adolescents (PFA). Then, content validation of the PFA was reviewed by 3 experts, using index of item-objective congruence (IOC) and content validity index (CVI). Subsequently, the reliability of the PFA was investigated through 49 respondents, using Cronbach’s α coefficient. Results : The PFA consists of 6 factors, including cognitive defusion, acceptance, flexible attention to the present moment, self-as-context, values, and commitment action. The results of this study showed that the content validity index (CVI) of the PFA ranged from .74 – 1 and the Cronbach’s α coefficientranged from .65 - .81 for 6 subscales. Conclusion : The content validity and reliability of the scale are acceptable or above, which is adequate for study further psychometric evaluation.