Lipid droplet biogenesis from specialized ER subdomains

Lipid droplet biogenesis from specialized ER subdomains – Lipid droplets (LDs) constitute a widely conserved fat storage compartment that plays a crucial role in cell physiology and metabolism. Growing evidence implicates LDs in many cellular processes, including the endoplasmic reticulum (ER) stress response, protein degradation, membrane trafficking and signal transduction, assembly of infectious viruses, and even for temporary storage of proteins. Defects in (...)