纳米晶
剂型
生物利用度
药品
纳米技术
灵活性(工程)
溶解
胶囊
材料科学
药理学
化学
医学
数学
有机化学
统计
生物
植物
作者
Daisuke Mori,Jalpa Makwana,Ekta Sakariya,Kiran Dudhat
出处
期刊:Current Drug Delivery
[Bentham Science]
日期:2020-08-06
卷期号:17 (6): 470-482
被引量:13
标识
DOI:10.2174/1567201817666200512104833
摘要
Drug nanocrystals offer an attractive approach for improving the solubility and dissolution rate of poorly soluble drugs which accounts for nearly 40 % newly discovered drug molecules. Both methods for manufacturing drug nanocrystals have high industrial acceptability for being simple and easy to scale which is evident from the number of approved products available in the market. Ability to modify multiple aspects of dosage form like bioavailability, release pattern and dosage form requirement along with flexibility in choosing final dosage form starting from the tablet, capsule, suspension to parenteral one, have made nanocrystal technology one of the very promising and adaptable technology for dosage form design.
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