益生元
嗜酸乳杆菌
益生菌
菊粉
食品科学
代谢综合征
安慰剂
医学
乳酸菌
胆固醇
化学
肥胖
内科学
生物
细菌
发酵
病理
替代医学
遗传学
作者
Douglas Xavier-Santos,Egidio Dorea Lima,Andréa Name Colado Simão,Raquel Bedani,Susana Marta Isay Saad
标识
DOI:10.1016/j.jff.2017.12.041
摘要
This study aimed to evaluate the impact of a synbiotic diet mousse containing Lactobacillus acidophilus La-5 and the prebiotics inulin and fructooligosaccharides on anthropometric and blood pressure measurements, biochemical, inflammatory, haematological, and immunological parameters of volunteers with metabolic syndrome (MetS). In a randomized, double-blind, placebo-controlled trial, forty-five volunteers with MetS were assigned into two groups, each receiving 40 g/day of: synbiotic diet mousse (SDM) (n = 23) and placebo diet mousse (PDM) without pro- and prebiotics (n = 22). All the evaluated parameters were measured at the beginning and after 8 weeks of intervention. The daily intake of SDM and PDM led to significant reductions of total cholesterol and HDL-cholesterol, as well as of immunoglobulins (A and M), and interleukin-1β in both groups (p < .05). These results suggest that the presence of the probiotic and prebiotic ingredients in the diet mousse did not show any additional effects on the parameters evaluated in volunteers with MetS.
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