Studies on Glycosides. IX

The two kinds of new glycoside, paeonoside and paeonolide, obtained from peony bark, were found to be β-glycosides and their hydrolysis was found to be different from that reported by Peron who stated that the extract solution of glycoside of peony bark was not affected either by emulsin or invertin. Examination of this point revealed that Peron's result must have been due to the presence of thymol added to the extract solution for antiseptic purpose. This showed that thymol had the power to inhibit hydrolysis of glycosides and that fact was confirmed by experiments with 8 kinds of glycoside, including paeonoside. It was also revealed that phenols other than thymol had the same inhibitive action on hydrolysis of glycosides, by testing 11 kinds of phenols.