Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide
作者
Amin Rostami‐Hodjegan,Helen Humphries,Zoe E. Barter,Amin Rostami‐Hodjegan,Yeo K Rowland
出处
期刊:The University of Manchester - Research Explorer [University of Manchester] 日期:2013-03-01