Tetrasubstituted Chromanone Synthesis by a Tandem Oxa‐Michael/Michael Addition Reaction of 2‐Hydroxyacetophenones and Alkynyl Nitriles

Abstract An efficient transition metal‐free approach for the synthesis of chroman‐4‐ones via double conjugate addition of 2‐hydroxyacetophenones on alkynyl nitriles utilizing NaH as a base has been realized. This operationally simple protocol offers library of 4‐chromanones in moderate to good yields.