Widespread 18F-FDG Uptake in Osseous Tuberculosis Without Pulmonary Tuberculosis

Abstract A 30-year-old man with a 5-month history of lumbar pain was hospitalized due to worsening pain and restricted mobility. CT and MRI scans indicated multiple vertebral destructions, prompting further assessment with 18 F-FDG PET/CT. PET/CT imaging showed widespread and avid 18 F-FDG uptake in the bones, mainly in the vertebrae. No other suspicious lesions were detected. Pathology subsequently confirmed the presence of Mycobacterium tuberculosis . This case illustrates 18 F-FDG PET/CT imaging of osseous tuberculosis, characterized by widespread 18 F-FDG accumulation without pulmonary tuberculosis.