Copper-based Superoxide Dismutase Enzyme Mimics: From Functional Models to Nanozymes

This chapter explores the role of superoxide dismutase (SOD) enzymes in protecting cells from oxidative stress by catalyzing the conversion of superoxide into oxygen and hydrogen peroxide. It examines the structure, function, and significance of SOD, along with the challenges associated with developing synthetic SOD mimics, particularly those based on copper complexes. This chapter highlights advancements in creating stable, selective, and efficient SOD mimics for potential therapeutic applications, with an emphasis on the development of nanozymes. These nanozymes offer enhanced stability and catalytic activity, making them promising candidates for treating oxidative stress-related diseases. This chapter concludes by addressing the challenges and prospects of SOD mimics and nanozymes in clinical applications.