医学
前列腺癌
横断面研究
生活质量(医疗保健)
心情
癌症
人口
癌症相关疲劳
内科学
老年学
物理疗法
精神科
病理
护理部
环境卫生
作者
Yoichiro Tohi,Takuma Kato,Tomoko Honda,Yu Osaki,Yohei Abe,Hirohito Naito,Yuki Matsuoka,Homare Okazoe,Rikiya Taoka,Nobufumi Ueda,Mikio Sugimoto
出处
期刊:Japanese Journal of Clinical Oncology
[Oxford University Press]
日期:2024-02-09
摘要
To investigate the prevalence of frailty and its effects on cancer-related fatigue and quality of life among patients with prostate cancer.In this cross-sectional study, questionnaires were administered to 254 outpatients who visited the Department of Urology at Kagawa University Hospital for prostate cancer; finally, 108 outpatients were analyzed. Frailty, cancer-related fatigue and quality of life were assessed using the G8 screening tool, Japanese version of the Brief Fatigue Inventory and Japanese version of the Short Form 8 Health Survey, respectively. We defined frailty based on a score ≤14 points and divided the patients into frailty and no-frailty groups. We also compared the severity of cancer-related fatigue and quality of life between groups.The prevalence of frailty among 108 outpatients was 63%. Older age correlated with frailty severity (P = 0.0007) but not cancer-related fatigue severity (P = 0.2391). The proportion of patients on treatment or with metastasis was not significantly different between groups. The frailty group had higher cancer-related fatigue severity (P = 0.004) and decreased levels of general activity, mood, walking ability, normal work and enjoyment of life, especially on the Brief Fatigue Inventory subscale. The frailty group had lower physical and mental quality of life than the no-frailty group or general population.The frailty rate for these patients increased with age, exceeding 60% regardless of the treatment status, and was associated with worsened cancer-related fatigue severity and reduced quality of life. Our study highlights the importance of assessing frailty when selecting treatment, especially in older patients.
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