Exosome therapy in female reproductive aging

As life expectancy continues to extend, the adverse effects of reproductive aging on female health have become progressively conspicuous. Despite the extant focus on symptom alleviation, a paucity of pharmaceutical interventions addresses the underlying causative factors. Exosome therapy, acknowledged for its relatively safe cell-free approach, emerges as a promising avenue. Notably, exosomes derived from stem cells exhibit comparable efficacy to their cellular counterparts. Nevertheless, extant methodologies for exosome production exhibit several limitations, particularly in achieving high-caliber, large-scale manufacturing. Consequently, this review is dedicated to elucidating the ongoing research endeavors and advancements of exosome therapy pertaining to the female reproductive aging.