纳米技术
DNA纳米技术
纳米载体
生物传感器
DNA
纳米医学
纳米生物技术
计算生物学
材料科学
药物输送
生物
纳米颗粒
遗传学
作者
Liwei Shen,Pengfei Wang,Yonggang Ke
标识
DOI:10.1002/adhm.202002205
摘要
Over the past few decades, DNA nanotechnology engenders a vast variety of programmable nanostructures utilizing Watson–Crick base pairing. Due to their precise engineering, unprecedented programmability, and intrinsic biocompatibility, DNA nanostructures cannot only interact with small molecules, nucleic acids, proteins, viruses, and cancer cells, but also can serve as nanocarriers to deliver different therapeutic agents. Such addressability innate to DNA nanostructures enables their use in various fields of biomedical applications such as biosensors and cancer therapy. This review is begun with a brief introduction of the development of DNA nanotechnology, followed by a summary of recent applications of DNA nanostructures in biosensors and therapeutics. Finally, challenges and opportunities for practical applications of DNA nanotechnology are discussed.
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