Green light relieves stress-induced anxiety-like behaviors via visual-to-prefrontal projections in mice

). Chemogenetic activation of this pathway mimics the anxiolytic effects of green light, whereas artificial inhibition of this pathway or pharmacological blockade of CRF receptor 1 (CRFR1) in the PrL abolishes green-light-induced anxiolysis in acute stress model mice. This study thus indicates a CRF-dependent neural mechanism underlying the anxiolytic effects of green light under stress conditions.