CLINICOPATHOLOGIC FEATURES OF POORLY DIFFERENTIATED ADENOCARCINOMA OF THE COLON

For recent 16 years, 623 cases of colon carcinoma were treated with resection in our surgical department. Fourteen of the 623 tumors, which account 2.2% of our series, were diagnosed as poorly differentiated adenocarcinoma. Clinicopathologic features of these poorly differentiated adenocarcinoma were investigated. Poorly differentiated adenocarcinoma had a strong likelihood of location in the right colon, deep invasion of tumor through the bowel wall or lymph node metastasis, compared to well differentiated adenocarcinoma. But, no hepatic metastasis was found in poorly differentiated ones. The cumulative 5- or 9-year survival rate after resection in patients with poorly differentiated adenocarcinoma was 51.3%, that after curative resection was 67.5%. These survival rates were similar to those in patients with well differentiated adenocarcinoma.