基因
心脏发育
基因表达
生物
人的心脏
哺乳动物心脏
内科学
解剖
细胞生物学
遗传学
医学
胚胎干细胞
出处
期刊:PubMed
[National Institutes of Health]
日期:1999-08-01
卷期号:35 (8): 1029-40
被引量:1
摘要
The data on the chamber-specific expression of cardiac genes in the animal and human heart are reviewed. The positional specification of atrial and ventricular gene expression observed in adults is initiated early during embryogenesis. The existence of a cascade of genes is assumed, beginning with genes whose products form an anterior-posterior gradient along the heart-forming regions or along the linear heart tube derived from these regions, and ending with genes that encode the contractile proteins and display chamber-specific expression.
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