Prospects for the combination of mechanochemistry and flow applied to catalytic transformations

The urge of developing modern alternatives regarding industrial production has led to the creation of novel techniques that help overcoming critical disadvantages from traditional batch mechanochemistry. One promising strategy includes the merging of flow processes with mechanochemistry. Two technologies are herein highlighted: twin-screw extrusion (TSE) and Impact (induction) in Continuous flow HEated Mechanochemistry (I-CHEM) allowing not only the industrial production of polymers, but also active pharmaceutical ingredients, synthesis of (nano)materials, and the obtention of high-added value products from biomass and wastes valorization.