PCL/Fucoidan nanofiber membrane loaded HP-β-CD/EGC inclusion complexes for food packaging based on self-assembly strategy

In this study, 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD)/Epigallocatechin (EGC) inclusion complexes were prepared by ultrasound-guided, and Polycaprolactone (PCL)/Fucoidan (FD) nanofiber membranes were rapidly prepared by electrospinning technology. The test results showed that the average diameter of the nanofiber film increased from 1429.11 to 1728.12 nm, the water vapor permeability was enhanced, the crystallinity was reduced, and the surface was hydrophilic. Infrared spectroscopy and thermal analysis showed that hydrogen bonds were formed between the inclusion complexes and PCL/FD nanofibrous membranes, which improved the thermal stability of the fibrous membrane. The membrane exhibited the sustained release characteristics of EGC within 240 h and exhibited excellent antibacterial properties in vitro and in vivo. These results indicated that the developed nanofibrous membranes have promising applications in food packaging.