Vanadia Nanozymes Inhibit Platelet Aggregation, Modulate Signaling Pathways and Prevent Pulmonary Embolism in Mice

nanozymes with specific and morphology-dependent GPx activity effectively inhibit the aggregation of human platelets and prevent pulmonary thromboembolism in mice. Crucially, the nanozymes do not lead to the unwanted side effect of bleeding, which is important in the development of more effective and safe antithrombotic agents.