A Co-catalytic nanosystem based on molybdenum disulfide and Prussian blue for synergistic chemodynamic and photothermal therapy through mitochondrial damage and ferroptosis

conversion and increasing ROS production. In addition, the photothermal properties of the material further amplify its therapeutic effects. In cell and animal models, this synergistic approach effectively induces mitochondrial damage and ferroptosis, thereby weakening the defenses of the cancer cells. This work provides a significant advancement in CDT, offering a more potent strategy for cancer therapy.