Objective: Researching the relationship between C-reactive protein and non- ST elevation acute coronary syndrome and its clinical meaning. Methods: Measuring C-reactive protein value of 62 patients with non- ST elevation acute coronary syndrome and 80 stable angina in the hospital from Jan 2000 to Jan 2005, observing the difference of two different type coronary heart disease. Results: There was obvious difference between non-ST elevation acute coronary syndrome and stable angina. Conclusion: C-reactive protein and non- ST elevation acute coronary syndrome have obvious relativity, can be the basis that discriminates non- ST elevation acute coronary syndrome for stable angina on clinic.