Discriminable meanings to the character of benign and malignant ascites brought by associated testing of VEGF、ADA and LDH

[Objective]To study the value of ADA,VEGF and LDH of ascites in the different diagnosis of the character of ascites.[Method]The levels of VEGF,ADA and LDH in ascites specimens from 13 tubercle,20 hepatocinhosis and 22 cancer ascites were tested.The levels of ADA in serum of the 55 cases were tested simultaneously.[Result]The level of ascites VEGF in cancer ascites was 42.07±404.90 pg/ml,which was significantly higher than that of the group of tubercule ascites (84.96±35.66 pg/ml) and that of the group of hepatocinhosis ascites(82.03±35.84pg/ml)(P 0.01).There was no obvious difference between the group of hepatocinhosis ascites and the group of tubercular ascites(P 0.05).The ratio of ADA in ascites to ADA in serum(PADA/SADA) in tubercular ascites(1.94±0.79) was higher than that in cancer ascites (0.93±0.08) and that of hepatocinhosis ascites(0.86±0.17)(P 0.01).The level of ascites ADA in tubercle ascites (25.68±4.73 U/L) was significandy higher than that in cancer ascites(12.48±6.17 U/L) and hepatocinhosis ascites(7.15±4.14 U/L)(P 0.01).The level of ascites LDH in tubercle ascites(218.08±70.78) U/L and cancer ascites(200.91±99.27) U/L were both higher than that in hepatocinhosis ascites(60.75±35.27) U/L(P 0.01).[Conclusion]VEGF in ascites is one of the important basis to the diagnosis of benign and malignant ascites;ADA and PADA/SADAof ascites have important reference to diagnosing tubercular ascites;LDH has definite value to identify the character of ascites which is exuding liquid or leaking liquid.