dry season indicating a marine condition. Higher Dissolved Oxygen values were recorded in the wet season than in the dry season.47.47% of the total organisms was sampled in the wet season while 52.53% was collected in the dry season. Species diversity was also higher in the dry season than the wet season. Tellina nymphalis, Clibanarius africana, and Penaus notialis sampled in the dry season were absent in the wet season. Only one species (Crassostrea gazar) sampled in the wet season was absent in the dry season. There was an indication of a general defaunisation of this lagoon for which reasons including pollution of the lagoon are plausible. [Journal of American Science 2010;6(3):8592]. (ISSN: 1545-1003)