转录因子
细胞生物学
生物
能量稳态
调节器
拟南芥
生长素
突变体
平衡
抄写(语言学)
信号转导
激酶
磷酸化
拟南芥
双分子荧光互补
串扰
作者
Prathibha Muralidhara,Christoph Weiste,Silvio Collani,Markus Krischke,Philipp Kreisz,Jan Draken,Regina Feil,Andrea Mair,Markus Teige,Martin J Müller,Markus Schmid,Dirk Becker,John E. Lunn,Filip Rolland,Johannes Hanson,Wolfgang Dröge-Laser
标识
DOI:10.1073/pnas.2106961118
摘要
Plants adjust their energy metabolism to continuous environmental fluctuations, resulting in a tremendous plasticity in their architecture. The regulatory circuits involved, however, remain largely unresolved. In Arabidopsis, moderate perturbations in photosynthetic activity, administered by short-term low light exposure or unexpected darkness, lead to increased lateral root (LR) initiation. Consistent with expression of low-energy markers, these treatments alter energy homeostasis and reduce sugar availability in roots. Here, we demonstrate that the LR response requires the metabolic stress sensor kinase Snf1-RELATED-KINASE1 (SnRK1), which phosphorylates the transcription factor BASIC LEUCINE ZIPPER63 (bZIP63) that directly binds and activates the promoter of AUXIN RESPONSE FACTOR19 (ARF19), a key regulator of LR initiation. Consistently, starvation-induced ARF19 transcription is impaired in bzip63 mutants. This study highlights a positive developmental function of SnRK1. During energy limitation, LRs are initiated and primed for outgrowth upon recovery. Hence, this study provides mechanistic insights into how energy shapes the agronomically important root system.
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