Enhance the Biological Properties of Commercial Pure Titanium with Bioactive Glass Coating by Pulsed Laser Deposition

Titanium is the most broadly employed implant material for the load bearing dental and the orthopedic uses due to its brilliant biological and mechanical characteristics. The aim of the present study is to assay the biological behavior of pure Titanium coated with a bioactive glass coating made by pulsed laser deposition. The coating characteristic and the biological behavior of coated specimens were assessed and compared with uncoated specimens. In vitro biological behavior including bioactivity, biocompatibility and antibacterial property was evaluated. The bioactivity of the specimens was assayed by immersion in a simulated body fluid for various times (7 and 14) days. Biocompatibility was assessed by MTT assay of L929 mouse fibroblast cells after 1, 3 and 5 days. Also, the antibacterial property was evaluated against S. aures by optical density method. The obtained results revealed that the pulsed laser deposited bioactive glass coating significantly improved the potential of Titanium for dental and orthopedic applications.