Gastritis cystica profunda in 15 cases

Objective To investigate the clinical characteristics and summarize the experiences on the diagnosis and treatment of gastritis cystica profunda (GCP).Methods Clinical data of 15 GCP patients,who were treated in the First and Second Affiliated Hospital of Zhengzhou University from January 2006 to January 2013,were retrospectively analyzed.Results GCP may present clinically as abdominal pain,bloating,emaciation,and GI bleeding.CT,electronic gastroscope,or ultrasonic endoscope shows that GCP consists of multiple cysts within a thickened submucosal layer.The submucosal pathological features can not be obtained by ordinary biopsy and snares.Of the 15 cases,proximal gastrectomy was performed in 4 cases,distal subtotal gastrectomy in 3 cases,1 case was treated with gastric wedge resection,and total gastrectomy was performed in 7 cases.Postoperative recovery was uneventful.13 cases were followed up for 2 years,and there was no evidence of recurrence.Conclusions GCP is an uncommon disease with unknown origin,and has no clinical characteristics,and has malignant potential.Postoperative prognosis is satisfactory. Key words: Gastritis;  Gastrectomy;  Endosonography