小梁网
青光眼
医学
IRIS(生物传感器)
眼科
同位
闭角型青光眼
瞳孔反应
开角型青光眼
验光服务
小学生
神经科学
解剖
生物
生物识别
计算机科学
计算机安全
作者
Zhi Da Soh,Sahil Thakur,Shivani Majithia,Monisha E. Nongpiur,Ching‐Yu Cheng
标识
DOI:10.1136/bjophthalmol-2020-316075
摘要
Glaucoma is a leading cause of irreversible visual impairment, and primary angle closure glaucoma (PACG) affects Asians disproportionately. Whereas advances in ocular imaging have identified several anatomical risk factors, our ability to predict PACG still requires considerable improvement. The iris plays a crucial role in the pathophysiology of angle closure disease, either through a mechanical or vascular mechanism. Irises of closed-angle eyes inhibit vastly different structural constituents as compared with those of open-angle eyes, thereby effecting variations in biomechanical properties and iris fluid conductivity. The clinical consequences include a smaller change in iris volume on pupil dilation in closed-angle eyes, thereby bringing the iris and trabecular meshwork closer in apposition. In this review, we summarise the potential role of the iris in the pathogenesis of angle closure disease.
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