Aberrant Hemispheric Asymmetry to a Contrast Illusion is Associated With Schizophrenia: A Principal Component Analysis of Event Related Potentials

The contrast of a visual target can appear suppressed in the presence of surrounding stimuli—an illusion that is sensitive to similarity between center and surround (e.g. their relative orientation; aka orientation dependent surround suppression [ODSS]). Evidence suggests that patients with schizophrenia have reduced ODSS relative to healthy controls (HC). The present study examined differences in neurophysiological response between SZ and HC during an ODSS task.