农药
杀虫剂
药物发现
计算生物学
生物
化学
生物技术
生物信息学
农业
生态学
作者
Xiangyang Li,Xue Yang,Xiaodong Zheng,Miao Bai,Deyu Hu
摘要
Molecular targets play important roles in agrochemical discovery. Numerous pesticides target the key proteins in pathogens, insect, or plants. Investigating ligand-binding pockets and/or active sites in the proteins’ structures is usually the first step in designing new green pesticides. Thus, molecular target structures are extremely important for the discovery and development of such pesticides. In this manuscript, we present a review of the molecular target structures, including those of antiviral, fungicidal, bactericidal, insecticidal, herbicidal, and plant growth-regulator targets, currently used in agrochemical research. The data will be helpful in pesticide design and the discovery of new green pesticides.
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