期刊:Organic chemistry frontiers [The Royal Society of Chemistry] 日期:2020-11-24卷期号:7 (23): 3868-3873被引量:9
标识
DOI:10.1039/d0qo00972e
摘要
The dual alkylation of the C(sp3)–H bond of cyclic α-methyl-N-sulfonyl imines has been achieved through the piperidine-promoted cascade condensation/[1,5]-hydride transfer/cyclization sequence from cyclic α-methyl-N-sulfonyl imines and o-aminobenzaldehydes in trifluoroethanol, providing structurally diverse 3-cyclic N-sulfonyl imine substituted tetrahydroquinolines in good yields with excellent diastereoselectivities.