化学
喹啉
萘醌
芳基
乙醇
催化作用
一锅法合成
有机化学
戒指(化学)
组分(热力学)
组合化学
物理
热力学
烷基
作者
Saiedeh Kamalifar,Hamzeh Kiyani
标识
DOI:10.2174/1385272823666191108123330
摘要
: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.
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