特发性肺纤维化
半乳糖凝集素-3
医学
博莱霉素
肺纤维化
纤维化
肌成纤维细胞
转化生长因子
癌症研究
支气管肺泡灌洗
肺
免疫学
病理
内科学
化疗
作者
Alison C. MacKinnon,Michael Gibbons,Sarah L. Farnworth,Hakon Leffler,Ulf J. Nilsson,Tamara Delaine,A. John Simpson,Stuart J. Forbes,Nik Hirani,Jack Gauldie,Tariq Sethi
标识
DOI:10.1164/rccm.201106-0965oc
摘要
This study identifies galectin-3 as an important regulator of lung fibrosis and provides a proof of principle for galectin-3 inhibition as a potential novel therapeutic strategy for IPF.
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