Peroxidase-Catalyzed Oxidative Phenolic Coupling of Some Tripeptides Containing Tyrosine and Hydroxyphenylglycine Residues

Several tripeptides containing tyrosine or its mono or dichloro derivative; glycine; and 4-hydroxyphenylglycine or its monochloro derivative were prepared. They were subjected to horseradish peroxidase (HRP)-catalyzed oxidative phenolic coupling. Only the products of intermolecular reaction, primarily C-O and C-C coupled dimers, were obtained.