Genomics research on Chinese mitten crab, Eriocheir sinensis was developed in recent years. Nucleotide sequences of 13 genes of Chinese mitten crab were analyzed, of which amino acids sequences of 8 proteins or its subunit were obtained by conceptual translation. Some study on microsatellite sequences and express sequence tags were also included. Generally, the genomics study on Chinese mitten crab is at its initial stage. To build the foundation for genetic improvement of Chinese mitten crab, more extensive efforts should be taken on its genomics study, especially on the structure and function of some important functional genes.